Along with cycle of the seasons, various subtle changes of human skin occur, which can be well adapted to the various seasonal climate changes. Spring always makes people feel the joy of new life, and also is the the best time for skin care. So, in this post we talk about something about “Epigenetics and Skin”.
As we know, throughout life, environmental conditions and diets have influences on the skin, and even may cause various skin disorders by changing gene expression pattern. Recent studies indicate that exposure to specific phytochemicals from the diet or direct skin contact, can affect gene expression via reversible epigenetic mechanisms and then is recorded in our “epigenome”. For example, lesional skin in psoriasis is found to be accompanied by changes in DNA methylation. The suggested mechanism is that our dietary epigenetic imprint superposed on our genome may act on skin-related regulation by affecting DNA methylation, chromatin structure and gene expression, which provide a new direction for skin disorders.
For their epigenetic effects, nutritional, botanical or phytopharmaceutical compounds may also be applied in stem cell differentiation, wound healing, skin regeneration, tissue homeostasis, or “correct” epigenetic marks responsible for inflammatory skin disorders and ageing.