With the increasing deepening of the study, nutrition and epigenetics display a wider relationship than confirmed by experiments. Within the ecosystem, epigenetics is the basis for continual transformation of almost every biological process of diverse plants and animals, which is required for adaptation to a dynamic environment.
Since food is essential for survival of all living beings, >60% of deaths are related to how, and what, we eat, rather than to environmental triggers. Nutritional deficits during pregnancy may result in greater risk of transgenerational pathologies, cause by dysfunctional epigenetic regulatory activity of fetal developmental genes. Recent studies indicate that specific nutrients required for metabolic methylation pathways can directly affect the epigenome to a greater degree than those driving DNA methylation/histone modifications. For example, tryptophan and niacin, obtained from food, are required for nicotinamide adenine dinucleotide-mediated poly (ADP-ribosylation) of histones or DNA repair, and further affect global methylation and expression of DNMT1, DNMT3a, and DNMT3b. The macromolecular composition of the diet also influences chromosomal stability that diet of caloric restriction is found to positively influence epigenetic stability in adults and reduces incidence of diseases.
In summary, keep healthy is very important through the summer, first, let’s start from a reasonable meal.